Rapidly obtain sections as skinny or thick as your software requires, with no stressing about dropping or distorting precious tissue samples.
Our convert-vital SmartBatch+ system combines electrophoretic tissue clearing and immunolabeling into 1 large-throughput unit.
Antibodies may perhaps choose months to diffuse as a result of only some millimeters of tissue, which has a steep labeling gradient from area to Main.
Megatome is suitable for precision: the blade vibrates at the next frequency and bigger amplitude vary than other microtomes, and encompasses a one of a kind deflection Regulate system.
SE uses a rotational electric powered industry to disperse remarkably electromobile molecules (for example antibodies or surfactant micelles) through a porous sample without having harmful electrically charged buildings throughout the tissue. This permits 2-4 working day clearing of intact organs,
Our preformulated EasyIndex Remedy raises and homogenize the refractive index of delipidated tissue samples, rendering them completely transparent. This enables light penetration into the sample and makes sure the acquisition of significant-resolution, in-emphasis impression knowledge.
Megatome is often a novel microtome that enables for high-precision sectioning of a variety of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with minimal tissue destruction and knowledge reduction.
It’s time to enhance your microtome to Megatome. With correct substantial-frequency slicing for an unmatched choice of sample measurements and types – from organoids and tumors megatomi.com to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized for various programs.
Absolutely delipidate full mouse brains or comparably sized samples in only one day with SmartBatch+, or in one week with our passive clearing kit.
Docset generation needs at minimum amount two alternatives: the identify in the docset and the location on the Javadoc data files to include while in the docset.
This will likely produce a docset named Sample in The present Listing. Docset creation is often customized with optional arguments:
Protect avoids the variability of hydrogel embedding and the information reduction from PFA preservation, preserving specimens for numerous rounds of processing.
--displayName: Will set the title as demonstrated in Sprint. This is handy should you develop a docset with identify SampleProject but Screen name Sample Challenge rather. This environment will default to the value of --title if omitted.
Our novel SHIELD tissue preservation approach forms intramolecular bonds employing polyfunctional, flexible epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.